Dermatology

P.L.E.A.S.E.®

Boost dermatologic treatments to a new level of efficacy

The P.L.E.A.S.E.® Professional system enables the delivery of bio-active agents of small to large molecular size to dermal layers by creating micro-pores of the desired size and depth almost painlessly. The creation of these channel-like pores happens without any significant trauma allowing the bio-active agent to permeate lateral and downwards into the tissue.

From medical to aesthetics and back

Epidermal drug delivery drove the development and established the P.L.E.A.S.E.® Professional system as the leading technology in this field. The border between a medical condition and an aesthetic desire is sometimes fluent. From active-ingredient cosmeceuticals to Photo Dynamic Therapy treatments and back to classical transdermal drug delivery, P.L.E.A.S.E.® improves all areas.

Ease of use, pre-set parameters will guide you


Each medical or aesthetic condition demands for a different quality of pores in regards to depth and density. The P.L.E.A.S.E.® Professional system offers pre-set parameters which guide you through the process.

Application fields